Date: 1606

An "evill and hinderance to wisdome ... is the confusion and captivitie of his passions, and turbulent affections, whereof he must disfurnish and free himselfe, to the end he may be emptie and neate, like a white paper, and be made a subject more fit to receive tincture and impressions of wisdome...

— Charron, Pierre (1541-1603); Lennard, Sampson (d. 1633)

Date: 1691

"The Brain, which is the principle of all Sense and Motion, the Fountain of the Animal Spirits, the Chief Seat and Palace Royal of the Soul; upon whose security depends whatever Privilege belongs to us as Sensitive or Rational Creatures."

— Ray [formerly Wray], John (1627–1705)