Date: 1644, 1647

"Sensory awareness comes about by means of nerves, which stretch like threads from the brain to all the limbs, and are joined together in such a way that hardly any part of the human body can be touched without producing movement in several of the nerve-ends that are scattered around in that area"

— Descartes, René (1596-1650)

Date: 1656

"It is impossible, Lady, except you should alter the Fabrick of his mind, unbend its appetite, or give it new desires; for as long as the divine soul creating breath, is clad with different disposing matter, and cast in several moulds, there will be Wise and Fooles."

— Anonymous